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| NEW STUDY SUGGESTS CONCORD GRAPE JUICE MAY PROVIDE PROTECTION AGAINST BREAST CANCER
Natural compounds in Concord grapes protected human breast cells from DNA damage
from environmental carcinogen CONCORD, MASS., July 30, 2007 – Every three minutes, a woman in the United States is
diagnosed with breast cancer1. While factors like age and heredity contribute significantly to a
woman's likelihood of contracting this disease, lifestyle and nutrition choices may also play a
role. One dietary choice that may help provide protection against breast cancer is a glass of 100
percent grape juice made from deep purple Concord grapes. According to a new study, published in the current issue of the Journal of Medicinal
Foods, natural compounds in Concord grape juice protected healthy human breast cells from
DNA damage. Healthy human breast cells were exposed in a test tube to an environmental
carcinogen, benzo(a)pyrene, that is able to initiate a chain of events leading to breast cancer.
However, the introduction of Concord grape juice compounds blocked the connection of the
carcinogen to the DNA of the healthy cells. "The purple grape compounds demonstrated the capacity to inhibit DNA adduct
formation as well as to increase the activity of enzymes that metabolize and detoxify
carcinogens, and suppress potentially cancer-causing oxidative stress," said Dr. Keith Singletary,
nutrition professor and lead researcher at the University of Illinois. "These new data suggest that
anthocyanins present in Concord grape juice, as well as some other fruits and juices, warrant
further study for their breast cancer chemopreventive potential." This research is the latest to suggest that Concord grape juice may be of value in
maintaining breast health by suppressing oxidative stress and inhibiting DNA damage to cells
that can lead to the initiation of cancer, or in helping to slow the progression of breast cancer by
slowing the multiplication of cancer cells. Diets high in natural antioxidants have been associated
with a reduced risk of some types of cancers, and Welch's 100% Grape Juice made from
Concord grapes is particularly high in anthocyanins, potent natural antioxidants that give the
juice its characteristic deep purple color. At the same time, drinking Concord grape juice can be good for the heart – much like red
wine. And so, with the link between alcohol consumption and breast cancer causing concern for
some women, drinking 100 percent grape juice made from Concord grapes can help your heart
and perhaps your breast health. Welch Foods Inc. is committed to supporting independent research exploring the role of
Concord grape juice in a healthy lifestyle, and provided the Concord grape juice compounds for
this study. 1 American Cancer Society, "Detailed Guide: Breast Cancer," 2006 ####
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